Reading Diary 3
Reading Diary 3
5 null terms
- attributable
- Attributable to somebody/something - probably caused by the thing mentioned.
- Example: Whereas some were attributable to subtype-specific sequence variation that influenced epitope-HLA binding, others were attributable to differential mutational barriers to immune escape.
N. N. Kinloch et al., “Genotypic and Mechanistic Characterization of Subtype-Specific HIV Adaptation to Host Cellular Immunity,” Journal of Virology, vol. 93, no. 1, Jan. 2019, doi: 10.1128/jvi.01502-18.
- en: приписываемый, относящийся
- elucidation
- The act of making something clearer by explaining it more fully.
- Example: The identification of HIV polymorphisms reproducibly selected under pressure by specific HLA alleles, and the elucidation of their impact on viral function, can help identify immunogenic viral regions where immune escape incurs a fitness cost.
N. N. Kinloch et al., “Genotypic and Mechanistic Characterization of Subtype-Specific HIV Adaptation to Host Cellular Immunity,” Journal of Virology, vol. 93, no. 1, Jan. 2019, doi: 10.1128/jvi.01502-18.
- en: разъяснение, пояснение
- implication
- A possible effect or result of an action or a decision.
- Example: Experimental investigation of select examples of subtype-specific escape revealed distinct underlying mechanisms with important implications for vaccine design.
N. N. Kinloch et al., “Genotypic and Mechanistic Characterization of Subtype-Specific HIV Adaptation to Host Cellular Immunity,” Journal of Virology, vol. 93, no. 1, Jan. 2019, doi: 10.1128/jvi.01502-18.
- en: Последствия, эффект.
- inclusion
- The fact of including somebody/something; the fact of being included.
- Example: Overall, our results confirm HIV genetic context as a key modulator of viral adaptation to host cellular immunity and highlight the power of combined bioinformatic and mechanistic studies, paired with knowledge of epitope immunogenicity, to identify appropriate viral regions for inclusion in subtype-specific and universal HIV vaccine strategies.
N. N. Kinloch et al., “Genotypic and Mechanistic Characterization of Subtype-Specific HIV Adaptation to Host Cellular Immunity,” Journal of Virology, vol. 93, no. 1, Jan. 2019, doi: 10.1128/jvi.01502-18.
- en: Включение, присоединение, вхождение.
- rigorous
- done carefully and with a lot of attention to detail
- Example: Our study represents the first characterization of HLA-driven adaptation pathways in HIV subtypes A1 and D, which dominate in East Africa, and the first statistically rigorous characterization of differential HLA-driven escape across viral subtypes.
N. N. Kinloch et al., “Genotypic and Mechanistic Characterization of Subtype-Specific HIV Adaptation to Host Cellular Immunity,” Journal of Virology, vol. 93, no. 1, Jan. 2019, doi: 10.1128/jvi.01502-18.
- en: Строгий, тщательный, точный